Gingival Crevicular Fluid-An Eos of Biomarkers

نویسندگان

چکیده

GCF is a serum transudate or inflammatory exudate that derived from the periodontal tissues and can be collected at orifice within gingival crevice.(1) The potential diagnostic importance of fluid was recognized more than 60 years ago serious investigation dynamics production did not begin until late 1950s with reports Brill co-workers.(2,3) component derives primarily microvascular leakage. Additions to volume are made intercellular cellular cytoplasm. tissue constantly subjected mechanical bacterial aggregation.Resistance these actions provided by saliva, sulcular fluid, epithelial surface keratinisation initial stages inflammation.(4) origin,composition clinical significance crevicular have significantly helped us in understanding pathogenesis disease.The need find non-invasive test method periodontitis drew attention sulcus produced small quantities even completely healthy periodontium, its composition near similar blood plasma.

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ژورنال

عنوان ژورنال: Journal of Pharmaceutical Negative Results

سال: 2022

ISSN: ['0976-9234', '2229-7723']

DOI: https://doi.org/10.47750/pnr.2022.13.s09.097